July 31, 2025

Manuka Honey for Diabetic Patients
Exploring the Potential Benefits of Manuka Honey for Diabetic Patients: An Evidence-Based Review

Diabetes affects millions of people worldwide, and managing blood sugar levels can often feel like a constant balancing act. As more people seek natural remedies for blood sugar control, Manuka honey has sparked interest due to its potential health benefits. Known for its high methylglyoxal (MGO) content, 

Manuka honey is touted not just as a sweetener, but as a potential ally in diabetes management. While honey is still a form of sugar and must be consumed in moderation, research suggests that Manuka honey may offer several benefits for people with diabetes, beyond simply satisfying a sweet craving.

In this article, we’ll explore what science says about Manuka honey’s effects on blood sugar levels, wound healing, and its antioxidant and anti-inflammatory properties. We’ll also offer practical tips on how people with diabetes can safely incorporate this honey into their diet. Remember, studies suggest the potential benefits, and Manuka honey is not a cure for diabetes; it’s simply a healthier alternative to refined sugars that can support your overall health journey.

How Does Manuka Honey Compare to Refined Sugar?

How Does Manuka Honey Compare to Refined Sugar?

One key reason honey is often considered a “healthier” sweetener than refined sugar is its composition. Manuka honey, in particular, has a unique balance of natural sugars that are metabolized differently than those found in common table sugar. Here’s how it works:

How Manuka Honey’s Higher Fructose Content May Affect Blood Sugar Levels

Manuka honey contains a higher ratio of fructose to glucose compared to other honeys, making it sweeter than sugar. This is important because fructose is absorbed more slowly by the body, causing a slower rise in blood glucose compared to glucose or sucrose. The slower absorption is key to why honey may cause a gentler rise in blood sugar.

Manuka Honey’s Moderate Glycemic Index: What It Means for Blood Sugar Control

Manuka Honey’s Moderate Glycemic Index: What It Means for Blood Sugar Control

A food's glycemic index (GI) indicates how quickly it raises blood sugar levels. Manuka honey has a GI of around 54–59, which is lower than the GI of table sugar (~65) (Is Manuka Honey Fattening?). This lower GI means Manuka honey causes a slower rise in blood glucose and provides a more steady release of energy, whereas refined sugar can spike blood sugar quickly. In practical terms, using Manuka honey in place of sugar could lead to smaller blood sugar fluctuations – an important consideration for people with diabetes looking to maintain stable levels.

These qualities make Manuka honey a potentially healthier sweetener choice than standard sugar. In fact, one study in people with type 2 diabetes found that consuming honey led to only about one-third the rise in blood glucose compared to an equivalent amount of pure glucose (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC). 

This suggests that honey has a gentler effect on blood sugar. However, remember that honey is still a source of carbohydrates, so consuming too much will still raise blood sugar. The goal is to use it in moderation as a swap for other sugars, not as a free pass to eat sweets.

(For a detailed comparison of honey vs. sugar beyond just blood sugar effects, check out our article on Honey vs. Sugar – A Natural Sweetener Showdown, which highlights differences in calories, nutrients, and health impact.)

What Studies Suggest About Manuka Honey’s Role in Blood Sugar Control”

What Studies Suggest About Manuka Honey’s Role in Blood Sugar Control

Manuka honey has shown potential benefits for people with diabetes in clinical studies(Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Types of Diabetes – PMC). While individual results vary, here’s a summary of what research has suggested:

How Manuka Honey May Help Improve Fasting Blood Sugar and Support Weight Management

How Manuka Honey May Help Improve Fasting Blood Sugar and Support Weight Management

In an 8-week clinical trial, patients with type 2 diabetes who replaced their daily sugar intake with honey (about 70 grams per day) experienced positive changes. The honey group saw a 1.3% reduction in body weight and a 4% drop in fasting blood glucose compared to those who consumed an equivalent amount of table sugar (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC). 

patients with type 2 diabetes who replaced their daily sugar intake with honey (about 70 grams per day)

Cholesterol levels also improved: total and LDL (“bad”) cholesterol went down, while HDL (“good”) cholesterol went up in the honey group (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC). 

These changes suggest that using honey instead of refined sugar might benefit some metabolic parameters in people with diabetes. Researchers believe this could be due to honey’s different sugar profile and the presence of other bioactive compounds in honey.

How Manuka Honey May Contribute to Better Cholesterol and Lipid Profiles

Studies consistently show that honey consumption is linked to lower cholesterol levels. In the same trial mentioned earlier, participants who consumed honey daily had lower triglycerides and LDL cholesterol, and higher HDL levels compared to the control group. 

This is significant because people with diabetes often face increased cardiovascular risk, and improving cholesterol and triglyceride levels may help reduce that risk. The bioactive compounds in honey, including flavonoids and phenolic acids, may contribute to these beneficial effects.

Caution: How Manuka Honey May Affect Long-Term Blood Sugar Control (HbA1c)

While honey shows potential for improving certain metabolic markers, long-term glucose control (HbA1c) must also be considered. In the same extended honey study, although the honey group showed short-term benefits (lower fasting glucose), their HbA1c levels increased slightly over the 8-week period (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC). 

In other words, despite short-term improvements in glucose and weight, consuming honey daily at high doses did raise the long-term blood sugar indicator. This underscores a crucial point – moderation is key. Honey may be better than refined sugar, but eating large amounts of any sugar, even natural honey, can still worsen diabetes control over time. 

The increase in HbA1c observed suggests that while honey might be preferable to sugar, it isn’t a free ticket to indulge in sweets without limit.

How Manuka Honey’s Glycemic Impact May Affect Blood Sugar Control in Diabetics

Additional research confirms that honey has a gentler glycemic effect than glucose or sucrose. In one study, people with diabetes were given various carbohydrate foods (glucose, bread, rice, honey, etc.), and their blood sugar responses were measured. Honey produced a significantly lower blood sugar spike – roughly 32% of the spike caused by pure glucose (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC). 

Another trial with young adults with type 1 diabetes found that honey led to a smaller rise in blood glucose and insulin (C-peptide) compared to an equivalent amount of sucrose (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC). 

These findings support the idea that honey’s natural sugars are metabolized more gradually, likely due to the higher fructose content and the presence of other compounds that may slow absorption. For someone managing diabetes, this could translate into better post-meal blood sugar readings when using honey instead of table sugar in a meal or beverage.

In summary, clinical studies suggest that Manuka honey (and natural honey in general) may offer some metabolic advantages for people with diabetes when used in place of refined sugars. Slight weight reduction, improved cholesterol levels, and a lower post-meal glucose spike have all been observed. However, there is also evidence that excessive honey intake can raise long-term glucose markers, reminding us that portion size matters greatly. 

These outcomes paint a picture of honey as a potentially favorable sweetener for people with diabetes. It is not a miraculous treatment but possibly a “less bad” alternative to sugar that comes with some added health perks.

How Manuka Honey’s Antioxidants May Help Combat Oxidative Stress in Diabetes

How Manuka Honey’s Antioxidants May Help Combat Oxidative Stress in Diabetes

Why might Manuka honey impart benefits beyond just lower glucose spikes? One explanation lies in its rich antioxidant and anti-inflammatory properties

Diabetes is not merely a blood sugar issue; it’s also characterized by oxidative stress (damage from free radicals) and chronic inflammation, which contribute to complications like neuropathy, retinopathy, and heart disease. 

Manuka honey’s nutritional profile – particularly its high content of flavonoids and phenolic acids – could help address these factors.

Antioxidant Power of Manuka Honey

Research has shown that Manuka honey from New Zealand like Bees &Trees Manuka Honey, has one of the highest antioxidant capacities among different types of honey. The phenolic compounds in Manuka honey, including caffeic acid and quercetin, have been shown to neutralize free radicals, thereby potentially protecting tissues from damage. This is important for diabetics because the oxidative damage caused by high blood sugar can worsen existing complications.

Manuka Honey’s Role in Reducing Oxidative Stress and Inflammation in Diabetes

Studies suggest that honey can help lower oxidative stress and inflammation. In animal studies, honey supplementation led to increased antioxidant enzyme levels (such as glutathione peroxidase and catalase), as well as lower markers of oxidative damage. These effects can improve overall health and potentially reduce complications related to diabetes. In diabetic rats, honey also helped reduce insulin resistance, likely due to its anti-inflammatory action.

Antioxidant Benefits for Diabetics

By reducing oxidative stress and inflammation, Manuka honey might offer protection against diabetic complications. Although this is still an area of ongoing research, studies suggest that antioxidants in Manuka honey could help improve insulin sensitivity and protect blood vessels, nerves, and organs from damage. 

At the very least, using Manuka honey as a substitute for refined sugar offers an extra dose of antioxidants, which is a positive step toward better health.

Potential Anti-Inflammatory and Cardiovascular Benefits of Manuka Honey for Diabetics

Potential Anti-Inflammatory and Cardiovascular Benefits of Manuka Honey for Diabetics

Chronic inflammation is a hallmark of diabetes, contributing to insulin resistance, arterial plaque buildup, and diabetic complications. Manuka honey’s anti-inflammatory properties make it an attractive addition to the diet of someone managing diabetes.

Reducing Inflammatory Markers

Research suggests that Manuka honey may reduce levels of pro-inflammatory markers like C-reactive protein (CRP). One study observed that substituting honey for sugar led to a modest decrease in CRP (approximately 3%) in both healthy individuals and people with diabetes. 

Though small, this reduction in inflammation could have long-term benefits, as chronic inflammation is a key contributor to complications in diabetes. Honey’s ability to modulate inflammation might also have positive implications for heart health.

Cardiovascular Benefits

People with diabetes are at higher risk for heart disease, and anything that improves cholesterol profiles and reduces inflammation is valuable. Studies show that Manuka honey reduces LDL cholesterol and triglycerides while increasing HDL cholesterol. This is especially important since diabetic patients often experience high levels of LDL cholesterol, which can contribute to cardiovascular disease.

Insulin Sensitivity and Heart Health

In addition to reducing inflammation and improving lipid profiles, Manuka honey may enhance insulin sensitivity. Reducing inflammation is one of the pathways through which Manuka honey may improve insulin response and reduce blood sugar. As insulin sensitivity improves, blood glucose management becomes easier, and the risk of developing cardiovascular disease decreases .

Manuka Honey and Diabetic Wound Healing

Manuka Honey and Diabetic Wound Healing

One of the most remarkable benefits of Manuka honey, and one that is well-established in medical literature, is its ability to promote wound healing. This is especially significant for people with diabetes, who often suffer from slow-healing wounds and ulcers (due to poor circulation, nerve damage, and higher infection risk). 

Diabetic foot ulcers are a common and serious complication that can even lead to amputations if not healed. Manuka honey, when applied topically, has shown impressive results in treating these wounds:

The Potential of Manuka Honey in Accelerating Wound Healing for Diabetics

Manuka honey has been proven to accelerate wound healing. A randomized trial published in the International Wound Journal showed that Manuka honey-impregnated dressings healed diabetic foot ulcers in an average of 31 days, compared to 43 days for conventional dressings. 

This 12-day difference is significant, especially for people with diabetes who often face prolonged healing times. The study concluded that Manuka honey is an effective treatment for chronic diabetic ulcers.

Manuka Honey’s Antibacterial Action and Its Potential Role in Infection Prevention

Manuka honey’s broad-spectrum antibacterial properties are well-documented (Manuka Honey and Wound Healing in Diabetic Ulcers – PubMed). In the same trial, 78% of the honey-treated ulcers were infection-free within one week, compared to just 35% in the conventional treatment group. 

The MGO and other bioactive compounds in Manuka honey target bacteria and pathogens that might otherwise prolong wound healing. For diabetic foot ulcers, keeping the wound clean of infection is a critical part of the healing process.

Manuka Honey’s Potential in Regenerating Tissue and Supporting Wound Healing

In addition to infection control, Manuka honey supports tissue regeneration by stimulating the formation of new blood vessels and collagen production. This process helps wounds heal faster and reduces the risk of scarring. Honey also helps reduce swelling and pain around the wound, which improves overall patient comfort. Its osmotic effect pulls lymph fluid into the wound, bringing in nutrients that speed up tissue regeneration.

In short, Manuka honey serves as a multi-functional healing agent. It fights infection, reduces inflammation, promotes tissue growth, and speeds up healing. These qualities make it a highly effective remedy for diabetic wounds, offering a natural alternative to standard wound care treatments.

How to Use Manuka Honey Safely as Part of Your Diabetes Management

How to Use Manuka Honey Safely as Part of Your Diabetes Management

If you’re considering using Manuka honey to support your diabetes management, here are some practical tips for incorporating it safely into your diet:

  1. Replace Refined Sugar, Don’t Add It: The goal is to swap regular sugar for Manuka honey, not add honey on top of your regular sugar intake. For example, use a teaspoon of Manuka honey to sweeten your tea instead of sugar. By doing this, you’ll lower your overall intake of refined sugar and gain the benefits of Manuka’s nutrients.

  2. Watch Portion Size: While Manuka honey has a lower GI than table sugar, it’s still high in carbohydrates and calories. Stick to 1–2 teaspoons (5-10 grams) per serving, and track your blood sugar to ensure it stays within your target range. Always check your glucose levels after consuming honey to ensure it works well for you.

  3. Pair Honey with Protein or Fiber: To slow the absorption of sugars, consume Manuka honey with foods that contain fiber or protein, such as oatmeal or Greek yogurt. This will help reduce the impact of honey on blood glucose and help prevent spikes.

  4. Choose High-Quality Manuka Honey: For maximum benefits, use authentic UMF rated or MGO- labeled Manuka honey. The higher the rating/MGO value (e.g., UMF 10+, 15+, 20+ or MGO 300+, 550+, 830+), the more potent the antibacterial and antioxidant compounds.

  5. Monitor Your Blood Sugar: As with any change in your diet, it’s important to monitor your blood sugar levels after introducing Manuka honey. Everyone’s body reacts differently, so tracking your levels will help you see how honey affects your glucose.

  6. Do Not Forego Medical Treatment: Manuka honey is a complementary tool, not a substitute for prescribed diabetes medications or insulin. Always follow your healthcare provider’s advice, and use honey as part of a broader, balanced diabetes management plan.

  7. Consult Your Healthcare Provider: Before making any significant dietary changes, especially if you have a strict carb regimen, consult your doctor or dietitian. They can help you determine how Manuka honey fits into your personal diabetes care plan.

Conclusion

Conclusion

Manuka honey offers a natural sweetener with potential benefits for those with diabetes. Its lower glycemic index and unique composition mean it affects blood sugar more gently than refined sugar, which can contribute to steadier blood glucose management. 

Scientific studies (including human trials) have observed that replacing regular sugar with honey may lead to better weight control, improved cholesterol levels, and smaller post-meal sugar spikes. Moreover, the rich antioxidant and anti-inflammatory properties of Manuka honey address underlying issues in diabetes, like oxidative stress and inflammation. 

These properties might help protect against complications and improve insulin sensitivity over time.

One of the most compelling benefits is in the realm of wound care. Manuka honey’s proven ability to speed up healing and prevent infection in diabetic ulcers offers a tangible, practical health advantage that many conventional sweeteners (or even medications) can’t claim. 

It bridges the gap between food and medicine, exemplifying how a natural product can enhance wellness on multiple fronts.

However, it’s crucial to maintain a balanced perspective. Manuka honey is not a magic bullet for diabetes. It contains sugar and calories, and if overused, it can still raise blood sugar and HbA1c levels. 

The key is to use Manuka honey strategically – as a smarter substitute for other sugars and within the context of a healthy diet. When used in moderation, Manuka honey allows people with diabetes to indulge their sweet tooth a bit while potentially gaining extra health benefits like antioxidants, without the full negative impact of refined sugar.

In adopting Manuka honey as part of your wellness routine, think of it as one supportive tool among many. It works best in conjunction with mindful eating, regular exercise, and appropriate medical care. 

Sources (Peer-Reviewed Research & References):

  1. Yaghoobi et al., Journal of Medicinal Food – Effects of honey vs. sucrose in type 2 diabetics (noted improvements in weight and lipids, with a rise in HbA1c) (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC).

  2. Al-Waili, European Journal of Clinical Investigation – Honey caused lower blood glucose response compared to dextrose in diabetics (honey at 32% of glucose’s glycemic response) (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC).

  3. Samarghandian et al., Int J Endocrinol Metab – Review highlighting honey’s role in improving insulin resistance, oxidative stress, and inflammatory status in diabetes (Honey consumption is inversely associated with prediabetes among Chinese adults: results from the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) Cohort Study | British Journal of Nutrition | Cambridge Core).

  4. Molan & Rhodes, International Wound Journal – Clinical trial showing Manuka honey dressings sped up healing of diabetic foot ulcers (31 days vs 43 days) and increased infection clearance (Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers - PubMed).

  5. Yao et al., Food Research (2020) – Analysis of Manuka honey’s nutritional content, showing high fructose and phenolic content contributing to its lower GI and antioxidant capacity (Is Manuka Honey Fattening?) (The Powerful Anti-Oxidant Properties of Manuka Honey).

  6. Erejuwa et al., Molecules – Animal studies where Tualang honey supplementation improved antioxidant enzyme levels and reduced blood glucose in diabetic rats (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC) (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC).

  7. Albaradi et al., Saudi J Biol Sci (2019) – Combined honey and diabetes medication in rats enhanced antioxidant status and glycemic control, suggesting synergy (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC) (Honey and Diabetes: The Importance of Natural Simple Sugars in Diet for Preventing and Treating Different Type of Diabetes - PMC).

  8. Ahmed et al., Int Wound J. (2014) – Study on Manuka honey in diabetic ulcers confirming faster healing and effective infection control with honey dressings (What is Manuka Honey Good For? and 14 Mind-Blowing Uses).



New to Mānuka Honey? Click here to learn about the different MGO levels. Check it out